Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1998-10-15
2000-04-04
Geist, Gary
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514640, 514645, 564300, 564265, 549434, A61K 3134
Patent
active
060462329
ABSTRACT:
Disclosed are novel .alpha.-aryl-N-alkylnitrone compounds and pharmaceutical compositions containing such compounds. The disclosed compositions are useful as therapeutics for preventing and/or treating neurodegenerative, autoimmune and inflammatory conditions in mammals and as analytical reagents for detecting free radicals.
REFERENCES:
patent: 3666754 (1972-05-01), Minami et al.
patent: 3834073 (1974-09-01), Dorschner et al.
patent: 3849934 (1974-11-01), Dorschner et al.
patent: 3903049 (1975-09-01), Saltman et al.
patent: 3917700 (1975-11-01), Auerbach
patent: 5292746 (1994-03-01), Carr et al.
patent: 5352442 (1994-10-01), Proctor
patent: 5397789 (1995-03-01), Carr et al.
patent: 5455272 (1995-10-01), Janzen et al.
patent: 5532252 (1996-07-01), Carr et al.
patent: 5723502 (1998-03-01), Proctor
Besson, et al. Nonlinear Optics, 1993, 4, 181-190.
P. Proctor, Physiol. Chem. & Physics. (1974) 4, 349-360.
P. H. Proctor, et al., Physiological Chemistry and Physics and Medical NMR. (1984) 16, 175-195.
P. Proctor, CRC Handbook of Free Radicals and Antioxidants. (1989) 1, 209-221.
CA:131:85 abs of Drugs Aging by Durif 14(5) pp 337-345, 1999.
CA: 124:200109 abs of Virology by Algright 217(1) pp211-19, 1996.
CA:130:217477 abs of Lupus by Dooley 7 (9) pp 630-634, 1998.
CA:130:280743 abs of Eur J Immunol by Scotet 29(3) pp 973-985, 1999.
CA:130:89983 abs of Ziekenuisfarmacie by De Jong van den Berg 14(4) pp190-193, 1998.
CA:119:179060 abs of Clin Immunol Immunopathol by Dilvani 67 (3 Pt 1) pp 199-203, 1993.
Acession No. 1999:397013 abs of Graefe's Arch Clin Exp Ophthalmol 237(6) pp 508-512, 1999.
CA:122:160227 abs of J chem Soc Perkin trans 1 by Sivasubramanian 23 pp 3353-4, 1994.
CA:116:193591 abs of J Org Chem by Hinton 57(9) pp 2646-51, 1992.
CA:111:58194 abs of Chem Express by Kotake 3 (12) pp 715-18, 1988.
CA:109:149392 abs of Synthesis by Kloc 12 pp1084-7, 1987.
CA: 107: 115572 abs of Huaxue Xuebao by Chem 44 (9) pp 927-33, 1986.
CA:100:138667 abs of Liebigs Ann Chem 11 pp 1937-49, 1983.
Dykman Alina
Kelleher Judith A.
Levell Julian
Maples Kirk R.
Wilcox Allan L.
Centaur Pharmaceuticals, Inc.
Geist Gary
Vollano Jean F
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