.alpha.-aryl-.alpha.-hydroxy-.beta.-imidazolinyl-propionamides

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

5483491, 5483007, A61K 31415, C07D23306

Patent

active

053346106

ABSTRACT:
The present invention relates to novel .alpha.-aryl-.alpha.-hydroxy-.beta.-imidazolinyl-propionamides of the general formula (I) ##STR1## in which n, R.sup.1 to R.sup.4 and X have the meaning indicated in the description, to a process for their preparation and to their use in medicaments.

REFERENCES:
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patent: 4226876 (1980-10-01), Copp et al.
patent: 4284584 (1981-08-01), Findeisen
Hawkins, et al., J. Am. Chem. Soc. 71, 1949, pp. 2530-2531.
Ozawa, et al., J. Am. Chem. Soc. 107, 1985, pp. 3235-3245.
Roedig, et al., Tetrahedron vol. 33, 1977, pp. 2437-2440.
Kolasa, et al., J. Org. Chem., 1987, 52, pp. 4978-4984.

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