Alpha-amylase variants

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase

Reexamination Certificate

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C435S183000, C435S252300, C435S320100, C536S023200

Reexamination Certificate

active

07867746

ABSTRACT:
The invention relates to a variant of a parent Termamyl-like alpha-amylase, which variant exhibits altered properties, in particular reduced capability of cleaving a substrate close to the branching point, and improved substrate specificity and/or improved specific activity relative to the parent alpha-amylase.

REFERENCES:
patent: 5753460 (1998-05-01), Bisgard-Frantzen
patent: 5989169 (1999-11-01), Svendsen et al.
patent: 6022724 (2000-02-01), Svendsen et al.
patent: 6093562 (2000-07-01), Frantzen et al.
patent: 6204232 (2001-03-01), Borchert et al.
patent: 6297038 (2001-10-01), Frantzen et al.
patent: 6440716 (2002-08-01), Svendsen et al.
patent: 6673589 (2004-01-01), Borchert et al.
patent: 6867031 (2005-03-01), Bisgaard-Frantzen et al.
patent: 2001/0039253 (2001-11-01), Borchert et al.
patent: 2003/0170769 (2003-09-01), Svendsen et al.
patent: 2004/0038368 (2004-02-01), Borchert et al.
patent: 2004/0048351 (2004-03-01), Svendsen et al.
patent: 285123 (1988-05-01), None
patent: WO 90/11352 (1990-10-01), None
patent: WO 91/00353 (1991-01-01), None
patent: WO 94/18314 (1994-08-01), None
patent: WO 95/10603 (1995-04-01), None
patent: WO 95/26397 (1995-10-01), None
patent: WO 96/23873 (1996-08-01), None
patent: WO 96/23874 (1996-08-01), None
patent: WO 97/41213 (1997-11-01), None
patent: WO 98/26078 (1998-06-01), None
patent: WO 99/09183 (1999-02-01), None
patent: WO 01/88107 (2001-11-01), None
patent: WO 02/092797 (2002-11-01), None
Accession AAR72449. Dec. 1, 1995.
Chica et al. Curr Opin Biotechnol. Aug. 2005;16(4):378-84.
Sen et al. Appl Biochem Biotechnol. Dec. 2007;143(3):212-23.
Tsukamoto et al., “Nucleotide Sequence of the Malthohexaose-Producing Amylase Gene From an AlkalophilcBacillusSp. 707 and Structural Similarity to Liquiefying Type Alpha-Amylases”, Biochemical and Biophysical research Communications, Academic Press Inc. , vol. 151, No. 1, pp. 25-31 (1988).
Svensson, “Protein Engineering in the Alpha-Amylase Family: Catalytic Mechanism, Substrate Specificity, and Stability”, Plant Molecular Biology, vol. 25, pp. 141-157 (1994).
Holm et al., “Random Mutagenesis Used to Probe the Structure and Function ofBacillus stearothermophilusAlpha-Amylase”, Protein Engineering, vol. 3, No. 3, pp. 181-191 (1990).
Machius et al., “Crystal Structure of Calcium-DepletedBacillus licheniformisAlpha-Amylase at 2.2 A Resolution”. Journal of Molecular Biology, vol. 246, pp. 545-559 (1995).

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