Alpha-amylase mutants

Details Alpha-amylase mutants Alpha-amylase mutants

2011-06-14

2011-06-14

Saidha, Tekchand (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

C536S023200

Reexamination Certificate

active

07960161

ABSTRACT:
The invention relates to a variant of a parent Termamyl-like alpha-amylase, which variant has alpha-amylase activity and exhibits an alteration in at least one of the following properties relative to the parent alpha-amylase: substrate specificity, substrate binding, substrate cleavage pattern, thermal stability, pH/activity profile, pH/stability profile, stability towards oxidation, Ca2+dependency and specific activity.

REFERENCES:
patent: 5731280 (1998-03-01), Nielsen et al.
patent: 5736499 (1998-04-01), Mitchinson et al.
patent: 5824532 (1998-10-01), Barnett et al.
patent: 6143708 (2000-11-01), Svendsen et al.
patent: 6297038 (2001-10-01), Bisgard-Frantzen et al.
patent: 6410295 (2002-06-01), Andersen et al.
patent: 6436888 (2002-08-01), Svendsen et al.
patent: 6440716 (2002-08-01), Svendsen et al.
patent: 6642044 (2003-11-01), Svendsen et al.
patent: 6867031 (2005-03-01), Bisgard-Frantzen et al.
patent: 6887986 (2005-05-01), Svendsen et al.
patent: 7625737 (2009-12-01), Svendsen et al.
patent: 7713723 (2010-05-01), Thisted et al.
patent: 2002/0155574 (2002-10-01), Thisted et al.
patent: WO 90/11352 (1990-10-01), None
patent: WO 91/00353 (1991-01-01), None
patent: WO 95/10603 (1995-04-01), None
patent: WO 95/26397 (1995-10-01), None
patent: WO 95/35382 (1995-12-01), None
patent: WO 96/23874 (1996-08-01), None
Boel et al., Biochemistry, vol. 29, pp. 6244-6249 (1990).
Declerck et al., The Journal of Biological Chemistry, vol. 265, No. 26, pp. 15481-15488 (1990).
Machius et al., Journal of Molecular Biology, vol. 246, pp. 545-559 (1995).
Holm et al, Protein Engineering, vol. 3 pp. 181-191 (1990).
Declerck et al, The Journal of Biological Chemistry, vol. 265, No. 26, pp. 15481-15488 (1990).
Machius et al. “Crystal Structure of Calcium-depleted-Bacillus licheniformisα-amylase at 2.2 Å Resolution” J.Mol.Biol. 246:545-559 (1995).
Boel et al. “Calcium Binding in α-Amylases: An X-ray Diffraction Study at 2.1-Å Resolution of Two Enzymes fromAspergillus” Biochemistry 29:6244-6249 (1990).
Kaneko et al., Journal of General Microbiology, vol. 135, pp. 3447-3457, sequence alignment (1989).
Takkinen et al., Biochemical Journal, vol. 185, pp. 387-395, sequence alignment (1980).
Takkinen et al., Journal of Biological Chemistry, vol. 258, pp. 1007-1013, sequence alignment (1983).

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