.alpha.-Amylase inactivator, a process for its preparation, an a

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...

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2601125R, 435 68, 435 70, A61K 3702, C07C10352, C12P 2100, C12P 2102

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active

044514557

ABSTRACT:
What are disclosed are two peptides having .alpha.-amylase inactivator activity, a method for making the inhibitors, in combination, by culturing Streptomyces tendae 4158 or Streptomyces tendae HAG 1226, methods for separating the combination into its two components, and methods and compositions for treating diabetes, pre-diabetes, or adiposity by administration of such peptide .alpha.-amylase inhibitors.

REFERENCES:
patent: 4226764 (1980-10-01), Oeding et al.
patent: 4282318 (1981-08-01), Oeding et al.
Aschauer et al., Hoppe-Seyler's Z. Physical. Chem., 362(4), 1981, pp. 465-467.

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