Alpha-amylase assay and substrates for use therein

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving glucose or galactose

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435 15, 435 22, 435 25, 435 26, 435 97, 435 95, 127 29, C12Q 154, C12Q 158, C12Q 140, C12P 1918

Patent

active

043048544

ABSTRACT:
A maltodextrin phosphorylase limit dextrin in the presence of maltodextrin phosphorylase and inorganic phosphate, is used as a substrate for alpha-amylase, which initiates a series of enzymatic reactions resulting in a chromogen response which can be used to measure the concentration of alpha-amylase in a body fluid. A novel limit dextrin and its preparation also are described.

REFERENCES:
patent: 2891869 (1959-06-01), Langlors
patent: 4036697 (1977-07-01), Pierre et al.
Gillard et al., "Amylo-1,6-Glucosidase/4-.alpha.-Glucanotransferase: Use of Reversible Substrate Model Inhibitors to Study the Binding and Active Sites of Rabbit Muscle Debranching Enzyme", Biochem., vol. 16, No. 18 (1977), pp. 3978-3987.
Marshall et al., "Detection of Endo-Acting Carbohydrases, Particularly in the Presence of Exoenzymes Acting on Same Substrate", Anal. Biochem., vol. 43, (1971), pp. 316-321.
Nix et al., "A New Method for Determination of .alpha.-Amylase", Clin. Chem., vol. 24, No. 6, (1978), p. 1000.
Swartz et al., "Escherichia coli maltodextrin phosphorylase", Chem. Abstracts, vol. 67, No. 19, (1967), p. 8257, Abs. No. 87876v.
Walker, et al., "The Mechanism of Carbohydrase Action", Biochem. J., vol. 76, No. 2, (1960), pp. 264-268.
Hestrin, "Action Pattern of Crystalline Muscle Phosphorylase", J. Biol., vol. 179, pp. 943-954.
Kruger, "Changes in The Amylases at Hand Spring Wheat During Growth and Maturation", Cereal Chem., vol. 49, No. 4, (1972), pp. 379-390.
Huang, et al., "A Specific Sensitive Assay for .alpha.-amylase Utilizing Modified Starch as Substrate", Clin. Chem., vol. 22, No. 7, (1976), p. 1164.
Richter, et al., "A Kinetic UV Method for the Determination of .alpha.-amylase", Clin. Chem., vol. 19, No. 6, (1973), p. 644.
Strenk, et al., "Substrate Starches in a U.V. Method for Quantitation of Amylase Activity", Clin. Chem., vol. 24, No. 6, (1978), p. 1000.
Kruger et al., "The Use of Reduced .beta.-Limit Dextrin as Substrate i an Automated Amylase Assay," Cereal Chem., vol. 149, (1972), pp. 453-458.
Kerr, Chemistry and Industry of Starch, 2nd ed., (1950), Academic Press, Inc., N.Y., pp. 210, 212-214, 414.
Barman, Enzyme Handbook, Springer-Verlang, New York Inc., NY, (1969), pp. 302, 303, 562-564.
Bergmeyer, Methods of Enzymatic Analysis, Academic Press, Inc., N.Y. (1974), pp. 505-507, 890-894.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Alpha-amylase assay and substrates for use therein does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Alpha-amylase assay and substrates for use therein, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Alpha-amylase assay and substrates for use therein will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-568312

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.