.alpha.-Aminoboronic acid peptides

Details .alpha.-Aminoboronic acid peptides .alpha.-Aminoboronic acid peptides

1983-12-05

1985-02-12

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

2601125R, 514 18, 514 19, A61K 3700, A61K 3144, C07C10352

Patent

active

044990820

ABSTRACT:
Peptides comprising C-terminal .alpha.-aminoboronic acid residues are potent, reversible inhibitors of proteolytic enzymes.

REFERENCES:
patent: 4369183 (1983-01-01), Jones
Leinhard, Enzyme Inhibitors as Drugs, Sandler, Ed., (University Park Press, Baltimore, 1980), pp. 43-51.
Koehler et al., Biochemistry 10:2477 (1971).
Matteson et al., J. Am. Chem. Soc. 103:5241 (1981).
Lindquist et al., Arch. Biochem. Biophys. 160:135 (1974).
Lindquist et al., J. Am. Chem. Soc. 99:6435 (1977).
Powers et al., Biochim. Biophys. Acta. 485:156 (1977).
Kleinerman et al., Am. Rev. Resp. Dis. 121:381 (1980).
Janoff et al., Am. Rev. Resp. Dis. 121:1025 (1980).
Stone et al., Am. Rev. Resp. Dis. 124:56 (1981).
Powers et al., Biochem. Biophys, Res. Comm. 67:639 (1975).
Lestienne et al., J. Biol. Chem. 254:5219 (1979).
Teshima et al., J. Biol. Chem. 257:5085 (1982).
Yoshimura et al., J. Biol. Chem. 257:5077 (1982).
U.S. Patent Application Serial No. 558,361.

Affiliated with

Also associated with

Rating

.alpha.-Aminoboronic acid peptides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with .alpha.-Aminoboronic acid peptides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and .alpha.-Aminoboronic acid peptides will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1389087