.alpha.-(aminoalkyl)-arylacetic acid derivatives

Details .alpha.-(aminoalkyl)-arylacetic acid derivatives .alpha.-(aminoalkyl)-arylacetic acid derivatives

1985-11-13

1988-11-08

Milestone, Norma S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540597, 540598, 540602, 540607, 540610, 544 78, 544 82, 544121, 544130, 544131, 544141, 544357, 544360, 544364, 544365, 544372, 544389, 544399, 544400, 546187, 546189, 546193, 546194, 546226, 546238, 546239, 546256, 546264, 546265, 546281, 546335, 546337, 548524, 548540, 548568, 548573, 560 39, 560 43, 560251, 562444, 562452, 564165, C07D29518, C07D29514, C07D21356, C07D21355

Patent

active

047835370

ABSTRACT:
Novel .alpha.-aryl-.alpha.-(.omega.-aminoalkyl)-.alpha.-[hydroxy(aralkyl and cycloalkyl)]acetic acid derivatives and .alpha.-aryl-.alpha.-(.omega.-aminoalkyl)-.alpha.[alkanoyloxy(aralkyl and cycloalkyl)]acetic acid derivatives, such as N,N-dimethyl-2-(hydroxyphenylmethyl)-4-dimethylamino-2-phenylbutanamide, 2-(hydroxyphenylmethyl)-5-dimethylamino-2-phenylpentanenitrile, ethyl 2-(hydroxyphenylmethyl)-5-dimethylamino-2-phenylpentanoate, and N,N-dimethyl-2[(acetyloxy)phenylmethyl]-4-dimethylamino-2-phenylbutanamide , useful in the treatment of cardiovascular disease.

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