Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1987-10-01
1990-06-05
Lee, Mary C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530317, 530323, 530328, 530329, 530330, 530331, 530332, 514 11, 514400, 514 18, 514 15, 514 16, 514 17, 564153, C07K 508, A61K 3700
Patent
active
049314297
ABSTRACT:
Compounds characterized generally as .alpha.-aminoacyl .beta.-aminoactyl aminodiols are useful as renin inhibitors for the treatment of hypertension.
REFERENCES:
patent: 4782043 (1988-11-01), Boger et al.
Umezawa et al, J. Antibiot. (Tokyo), 23:259-262 (1970).
Gross et al, Science, 175:656 (1971).
Boger et al, Nature, 303 81 (1983).
Kokubu et al, Biochem. Biophys. Res. Commun., 118 929 (1984).
Castro et al, FEBS Lett., 167 273 (1984).
Hanson et al, Biochem. Biophys. Res. Comm., 132 155-161 (1985).
Hanson et al, Biochem. Biophys. Res. Comm., 146 959-963 (1985).
Marshall, Federation Proc., 35 2494-2501 (1976).
Burton et al, Proc. Natl. Acad. Sci. USA, 77 5476-5479 (1980).
Suketa et al, Biochemistry, 14 3188 (1975).
Swales, Pharm. Ther., 7 173-201 (1979).
Kokubu et al, Nature, 217 456-457 (1968).
Matsushita et al, J. Antibiotics, 28 1016-1018 (1975).
Lazar et al, Biochem. Pharma., 23 2776-2778 (1974).
Miller et al, Biochem. Pharma., 21 2941-2944 (1972).
Haber, Clinical Sciences, 59 7s-19s (1980).
Rich et al, J. Org. Chem., 43 3624 (1978).
Rich et al, J. Med. Chem., 23 27 (1980).
Haber, Clin. and Exper. Hyper., A5(7 & 8) 1193 (1983).
Baran John S.
Hanson Gunnar J.
G. D. Searle & Co.
Keane J. Timothy
Lee Mary C.
Matukaitis Paul D.
Whittenbaugh Robert C.
LandOfFree
.alpha.-aminoacyl .beta.-aminoacyl aminodiols as anti-hypertensi does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with .alpha.-aminoacyl .beta.-aminoacyl aminodiols as anti-hypertensi, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and .alpha.-aminoacyl .beta.-aminoacyl aminodiols as anti-hypertensi will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-491631