.alpha.-Amino substituted thioacetamides

Details .alpha.-Amino substituted thioacetamides .alpha.-Amino substituted thioacetamides

1974-03-18

1976-08-24

Wyman, Daniel E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260551S, 260465C, 26050121, 424320, C07C153063

Patent

active

039766837

ABSTRACT:
The invention relates to thioamides of formula I ##SPC1##
and acid addition salts thereof wherein R.sub.1 and R.sub.2 are selected from the group consisting of hydrogen, lower alkyl, and phenyl and R.sub.3 and R.sub. 4 are selected from the group consisting of hydrogen and lower alkoxy, with proviso that when R.sub.3 and R.sub.4 are both hydrogen at least one of R.sub.1 and R.sub.2 is other than hydrogen.

REFERENCES:
CA 56: 404c, "Compounds with Spasmolytic Activity," Klosa, 1961.
CA 51: 15579h, "Spasmolytically Active Substituted p-methoxyphenylacetamides," N. V. Neder, 1957.
CA 52: 1241i, "Spasmolytics," N. V. Neder, 1956.
CA: 14164d, "Some .alpha.-dialkylaminophenylacetonitriles," Morris et al., 1961.
CA 49: 13237g, "Antispasmodics," Janssen, 1954.
Medicinal Chemistry, Burger, Ed., Interscience, 2nd Ed., p. 492 (1960).

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