.alpha. Amino fluoro ketones

Details .alpha. Amino fluoro ketones .alpha. Amino fluoro ketones

1984-02-06

1985-05-21

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07C10352

Patent

active

045185280

ABSTRACT:
Novel .alpha. amino fluoro ketones, a method of their synthesis and a method for irreversibly inhibiting proteases is disclosed.

REFERENCES:
patent: 4153688 (1979-05-01), Dimicoli et al.
patent: 4438270 (1984-03-01), Bey et al.
Chem. Abstr., vol. 101, (1984), 7625v.
Chem. Abstr., vol. 100, (1984), 139590u.
Chem. Abstr., vol. 99, 49361b, (1983).
Chem. Abstr., vol. 97, 446c, (1982).
The Journal of Biological Chemistry 257, (1982), 10063-10068.
Biochimica et Biophysica Acta 485, (1977), 156-166.
Biochimica et Biophysica Acta 755, (1983), 151-154.
J. Mol. Biol., (1980), 139, 423-438.
Journal of Pharmaceutical Sciences, vol. 68, No. 6, Jun. (1979), 696-698.
Biochemistry, vol. 16, No. 13, (1977), 2942-2948.

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