.alpha.-amino-.alpha.(3-alkyl-phenyl)alkyl ethanoic acids wherei

Details .alpha.-amino-.alpha.(3-alkyl-phenyl)alkyl ethanoic acids wherei .alpha.-amino-.alpha.(3-alkyl-phenyl)alkyl ethanoic acids wherei

1991-08-19

1992-11-10

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

514114, 514119, 554 84, 558 83, 558190, 560 29, 560 30, 560 31, 560 32, 560 33, 560 38, 560 39, 560 41, 562 11, 562 15, C07F 938, C07F 940, A61K 3166

Patent

active

051623110

ABSTRACT:
The invention discloses certain substituted .alpha.-aminoacids having the formula ##STR1## where m and n are 1 or 2, and R, R.sub.1, R.sub.2, R.sub.3 and Y have various significances, which compounds are useful in treating epilepsy, disorders associated with excess GH or LH secretion, anxiety, schizophrenia, depression, CNS degenerative disorders, cerebral hypoxic conditions and stress-related psychiatric disorders.

REFERENCES:
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patent: 4657899 (1987-04-01), Rzeszotarski et al.
patent: 4761405 (1988-08-01), Rzeszotarski et al.
patent: 4918064 (1990-04-01), Cordi et al.
"Fatty Acids" edited by Klare S. Markley Part 1, Part 3, Part 5 1960, 1964, 1968, pp. 38-41, 118-241, pp. 3198-3199, pp. 1771-1957.
Applicants were provided with copies of reference in Ser. No. 07/499,155.
Chem. Pharm. Bulletin, vol. 32, No. 10, pp. 3918-3925 (1984).
Neurol. Neurobiol., pp. 231-234 (1988).
Chem. Abstracts 110:135709y (1989).

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