.alpha.-amino acids through catalytic reaction of CO and a hydro

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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548344, 548496, 548497, 560 34, 560 41, 560155, 562426, 562439, 562450, 562556, 562574, 562575, C07D20716

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active

047105747

ABSTRACT:
Disclosed is the hydrocarboxylation of defined enamides with CO and a compound ROH to make amino acids or amido esters, either of which can be hydrolyzed to .alpha.-amino acids.

REFERENCES:
Becker, Y. et al., J. Org. Chem., 45, 2145 (1980).
Barton, J., in Protective Groups in Organic Chemistry (McOmie, editor), Plenum Press, London, 1973, pp. 46-49.

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