.alpha., .alpha.-disubstituted aromatics and heteroaromatics as

Details .alpha., .alpha.-disubstituted aromatics and heteroaromatics as .alpha., .alpha.-disubstituted aromatics and heteroaromatics as

1992-09-30

1994-04-05

Brust, Joseph Paul

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

540522, 544294, 544296, 544319, 544331, 544333, 544357, 544405, 544336, 546256, 546268, 546269, 546270, 546271, 546272, 546274, 546285, C07D40108, C07D40308

Patent

active

053006429

ABSTRACT:
Cognitive defeciencies or neurological dysfunction in mammals are treated with .alpha.,.alpha.-disubstituted aromatic or heteroaromatic compounds. The compounds have the formula: ##STR1## or a salt thereof wherein X and Y are taken together to form a saturated or unsaturated carbocyclic or heterocyclic first ring and the shown carbon in said ring is .alpha. to at least one additional aromatic ring or heteroaromatic ring fused to the first ring;

REFERENCES:
patent: 3574232 (1971-04-01), Canas-Rodriguez et al.
patent: 4760083 (1988-07-01), Myers et al.
patent: 5173489 (1992-12-01), Earl et al.
Research Disclosures, 184, pp. 446-454 (1979); Adin et al.
J. Heterocyclic Chem., 19, pp. 1013-1016 (1982); Daisley et al.
Eur. J. Med. Chem.--Chem. Ther. 16(4), pp. 373-378 (1981); Ogata et al.

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