.alpha.-allenic-.alpha.-amino acids as enzyme inhibitors

Details .alpha.-allenic-.alpha.-amino acids as enzyme inhibitors .alpha.-allenic-.alpha.-amino acids as enzyme inhibitors

1985-10-21

1987-04-28

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

562557, 562561, 514419, 562567, 562571, 514510, 562574, 564164, 514538, 564197, 564198, 514542, 514547, 514549, 514562, 514563, 514564, 514565, 514566, 548104, 548344, 548495, 560 9, 560 10, 560 34, 560 39, 560 40, 560 41, 560153, 560169, 560170, 560171, 560172, 562426, 562443, 562444, 562445, 562446, 562450, 562556, A61K 31415, C07D23364

Patent

active

046615105

ABSTRACT:
Novel .alpha.-allenic-.alpha.-amino acids which are enzyme inhibitors of the suicide or k.sub.cat type are disclosed herein.

REFERENCES:
patent: 3946060 (1976-03-01), Metcalf et al.
patent: 3959356 (1976-05-01), Metcalf et al.
patent: 3960927 (1976-06-01), Metcalf et al.
patent: 4103089 (1978-07-01), Metcalf et al.
patent: 4147873 (1979-04-01), Metcalf et al.
patent: 4275220 (1981-06-01), Patchett et al.
patent: 4325877 (1982-04-01), Metcalf et al.
patent: 4347375 (1982-08-01), Patchett et al.
Black, D., et al., J. Chem. Soc. (C), pp. 283-287 (1968).

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