.alpha.-Alkylsulfobenzyl penicillins

Details .alpha.-Alkylsulfobenzyl penicillins .alpha.-Alkylsulfobenzyl penicillins

1973-11-20

1977-11-08

Coughlan, Jr., Paul M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424271, C07D49946

Patent

active

040575446

ABSTRACT:
Novel penicillins of the formula ##STR1## wherein R is a branched chain alkyl group of from 3 to 14 carbon atoms, and their pharmaceutically acceptable salts, are easily absorbed in the blood and tissues through oral administration and show excellent antimicrobial activity against Gram-positive and Gram-negative bacteria, particularly against microorganisms of the genus Pseudomonas, such as Pseudomonas aeruginosa.

REFERENCES:
patent: 3660379 (1972-05-01), Morimoto et al.
patent: 3697507 (1972-10-01), Frederiksen et al.
patent: 3748323 (1973-07-01), Hamanaka
patent: 3925362 (1975-12-01), Sugimoto et al.

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