.alpha.-[4-Oxoazetidin-1-yl]-acetic acid compounds useful as int

Details .alpha.-[4-Oxoazetidin-1-yl]-acetic acid compounds useful as int .alpha.-[4-Oxoazetidin-1-yl]-acetic acid compounds useful as int

1979-03-12

1981-08-11

Berch, Mark L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602393R, 2602454, 2603407, 2603409R, 544359, 546208, 546256, 546275, C07D70508, C07D40514, C07D40512, C07D40112

Patent

active

042833337

ABSTRACT:
Azetidine derivatives of the formula: ##STR1## wherein A is amino or substituted amino; COB is carboxy or protected carboxy; R.sup.1 is .dbd.C(CH.sub.3).sub.2, ##STR2## (R.sup.4 is alkyl, aryl or aralkyl); OR.sup.2 and OR.sup.3 independently or taken together with each other represent a ketal; Y is hydrogen or methoxy; Z is hydrogen or halogen, and a process for preparation thereof. Used as intermediates in the preparation of potent antimicrobials 1-oxadethiacephalosporins.

REFERENCES:
Yoshioka et al., Chem. Abs., 88, 169941k, (1978).

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