Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1990-11-30
1995-06-13
Patterson, Jr, Charles L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
530356, C12N 1512
Patent
active
054244080
ABSTRACT:
An isolated and substantially pure polynucleotide encoding 238 amino acids of the carboxy terminal end of the triple helical domain and all 233 amino acids of the carboxy terminal noncollageneous domain of the bovine .alpha.3 chain of type IV collagen. An isolated and substantially pure polynucleotide encoding 218 amino acids of the carboxy terminal noncollagenous domain of the human .alpha.3 chain of type IV collagen. Such polynucleotides are useful to express large amounts of proteins in vectors and such expressed proteins are useful to detect Goodpasture antibodies in blood and to remove Goodpasture antibodies from the bloodstream of patients suffering from Goodpasture syndrome.
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Hudson Billy G.
Morrison Karen E.
Reeders Stephen T.
Patterson, Jr Charles L.
The University of Kansas Medical Center
Yale University
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