Alpha-2-antagonistic substituted 4-fluoro-isoindolines

Details Alpha-2-antagonistic substituted 4-fluoro-isoindolines Alpha-2-antagonistic substituted 4-fluoro-isoindolines

1986-12-16

1988-10-11

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548316, 548482, A61K 31415, C07D40312

Patent

active

047771810

ABSTRACT:
Substituted 4-fluoro-isoindolines of the general formula I ##STR1## in which R denotes hydrogen or an acyl group, and their tautomeric forms and their acid addition salts have an alpha.sub.2 -antagonistic action.

REFERENCES:
patent: 4221798 (1980-09-01), Cohnen
patent: 4526897 (1985-07-01), Cohnen et al.
Arneimittel Forschung, 32, II, 1982, pp. 1534-1540.
Chemical Abstracts, vol. 102, 1985, Ref. 17146 z.
Chemical Abstracts, vol. 96, 1982, Ref. 52154 e.
Chemical Abstracts, vol. 99, 1983, Ref. 99175 q.

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