.alpha.-1-antichymotrypsin, analogues and methods of production

Details .alpha.-1-antichymotrypsin, analogues and methods of production .alpha.-1-antichymotrypsin, analogues and methods of production

1989-06-23

1992-01-07

Wax, Robert A.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

424 852, 424 854, 435 6, 435 703, 4352351, 435 692, C07K 300, A61K 7035, A61K 4505, C12P 2102

Patent

active

050793365

ABSTRACT:
The invention provides .alpha.-1-antichymotrypsin and protein preparations comprising human .alpha.-1-antichymotrypsin produced by E. coli cells transformed with a DNA sequence encoding human .alpha.-1-antichymotrypsin. The invention also provides methods for producing .alpha.-1-antichymotrypsin. The invention further provides analogues of .alpha.-1-antichymotrypsin that exhibit antichymotrypsin, anti-trypsin and anti-thrombin activity and methods of producing the analogues.

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