Aloctin A

Details Aloctin A Aloctin A

1978-11-20

1980-09-30

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424177, C07G 700, A61K 3700

Patent

active

042254868

ABSTRACT:
A glycoprotein isolated from Aloe, a plant belonging to Liliaceae, having a molecular weight of 1.8.times.10.sup.4 and a ratio of protein to sugar of 8 to 2 by weight; yielding only a single band upon SDS-polyacrylamide gel electrophoresis without 2-mercaptoethanol treatment and yielding two discrete bands upon SDS-polyacrylamide gel electrophoresis with 2-mercaptoethanol treatment; having hemagglutinating and cytoagglutinating activity for transformed cells; having mitogenic activity for lymphocytes, cap forming activity for lymphocytes and cultured transformed cells using fluorescence labeled glycoprotein; having binding reactivity with some types of serum proteins; and having the capability of activating complement components.

REFERENCES:
patent: 3362829 (1968-01-01), Landfried, et al.
Chem. Abstr., 73, 1970, 75501e.

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