Allyl amine MAO inhibitors

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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546229, 549 49, 549 55, 549 74, 549469, 549491, 564383, 568335, 568775, 548511, 548560, A01N 3302

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044541589

ABSTRACT:
Compounds of the formula ##STR1## wherein: R is phenyl, phenyl monosubstituted, disubstituted, or trisubstituted by (C.sub.1 -C.sub.8) alkyl, (C.sub.1 -C.sub.8)alkoxy, hydroxy, chlorine, bromine, iodine, fluorine, trifluoromethyl, nitro, (C.sub.1 -C.sub.6)alkylcarbonyl, benzoyl, or phenyl; 1-, or 2-naphthyl; 1-, 2-, or 3-indenyl; 1-, 2-, or 9-fluorenyl; 1-, 2-, or 3-piperidinyl; 2- or 3-pyrrolyl; 2- or 3-thienyl; 2- or 3-furanyl; 2- or 3- indolyl; 2- or 3-thianaphthenyl; or 2- or 3-benzofuranyl;

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Schulze, K. et al., Z. Chem. 17 58 (1977).
Rando, R. J. Am. Chem. Soc. 95 4438 (1975).
Rando, R. et al., Molecular Pharmacology 13 1005 (1977).
Boor, P. et al., Amer. J. Pathol. 100, 739 (1980).
Krantz, A. et al., Drug Action and Design: Mechanism-Based Enzyme Inhibitor, pp. 145-174 Ekener N. Holland N.Y. 1979.

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