Allosteric modulators of the NMDA receptor and their use in the

Details Allosteric modulators of the NMDA receptor and their use in the Allosteric modulators of the NMDA receptor and their use in the

1995-03-30

1998-12-29

Allen, Marianne P.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 18, 530326, 530330, A61K 3810, A61K 3807, C07K 510, C07K 700

Patent

active

058542175

ABSTRACT:
Novel compounds and compositions for modulating NMDA receptor function comprising Conantokin-G and derivatives thereof; methods for modulating NMDA receptor function and methods for treating neuropsychopharmacological disorders, using the novel compounds and compositions of the invention; and a method for screening compounds capable of binding to a novel allosteric modulatory site, are described.

REFERENCES:
patent: 5051403 (1991-09-01), Miljanich et al.
patent: 5523323 (1996-06-01), Maccecchini
patent: 5559095 (1996-09-01), Miljanich et al.
Hernandez, J.-F. et al., J. Cell Biochem. Suppl. 0 (14 Part C), 242, 1990. and attached presentation slide copies.

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