Allosteric modulators of the NMDA receptor and their use in the

Details Allosteric modulators of the NMDA receptor and their use in the Allosteric modulators of the NMDA receptor and their use in the

1998-09-03

2000-08-29

Allen, Marianne P.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530326, A61K 3804

Patent

active

061108944

ABSTRACT:
Novel compounds and compositions for modulating NMDA receptor function comprising Conantokin-G and derivatives thereof; methods for modulating NMDA receptor function and methods for treating neuropsychopharmacological disorders, using the novel compounds and compositions of the invention; and a method for screening compounds capable of binding to a novel allosteric modulatory site, are described.

REFERENCES:
patent: 5051403 (1991-09-01), Miljanich et al.
patent: 5559095 (1996-09-01), Miljanich et al.
patent: 5830908 (1998-11-01), Maccecchini
patent: 5844077 (1998-12-01), Saydoff
Hernandez, J.-F. et al., J. Cell Biochem. Suppl. O(14 Part C), 242, 1990, and attached presentation slide copies.

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