Allosteric modifiers of hemoglobin useful for decreasing oxygen

Details Allosteric modifiers of hemoglobin useful for decreasing oxygen Allosteric modifiers of hemoglobin useful for decreasing oxygen

1995-01-18

1998-03-24

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560 43, 562434, 562455, C07C22904, C07C22934, C07C22942

Patent

active

057314543

ABSTRACT:
A family of compounds has been found to be useful for right-shifting hemoglobin towards a low oxygen affinity state. The compounds are capable of acting on hemoglobin in whole blood. In addition, the compounds can maintain the oxygen affinity in blood during storage and can restore the oxygen affinity of outdated blood.

REFERENCES:
patent: 5122539 (1992-06-01), Abraham et al.
patent: 5290803 (1994-03-01), Abraham et al.
patent: 5382680 (1995-01-01), Abraham et al.
patent: 5432191 (1995-07-01), Abraham et al.

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