Allosteric modifiers of hemoglobin

Details Allosteric modifiers of hemoglobin Allosteric modifiers of hemoglobin

1998-03-13

1999-02-16

Geist, Gary

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

562426, 562429, 562431, 562432, 562442, 562443, 562867, 560 11, 560 12, 560 15, 560 16, 560 17, 560 19, 560 37, 560 43, C07C22900, C07C32100, C07C31500, C07C30300

Patent

active

058722823

ABSTRACT:
A family of compounds has been found to be useful for right-shifting hemoglobin towards a low oxygen affinity state. The compounds are capable of acting on hemoglobin in whole blood. In addition, the compounds can maintain the oxygen affinity in blood during storage and can restore the oxygen affinity of outdated blood.

REFERENCES:
patent: 4151303 (1979-04-01), Witte et al.

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