Allosteric modifiers of hemoglobin

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

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560 45, C07C22940

Patent

active

055918921

ABSTRACT:
A family of compounds has been found to be useful for right-shifting hemoglobin towards a low oxygen affinity state. The compounds are capable of acting on hemoglobin in whole blood. In addition, the compounds can maintain the oxygen affinity in blood during storage and can restore the oxygen affinity of outdated blood.

REFERENCES:
patent: 4980372 (1990-12-01), Nakai et al.
patent: 5087743 (1992-02-01), Janssen et al.

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