Allergens and antibodies from allergen extracts and pooled serum

Details Allergens and antibodies from allergen extracts and pooled serum Allergens and antibodies from allergen extracts and pooled serum

1982-10-26

1986-01-14

Marantz, Sidney

Chemistry: analytical and immunological testing

Involving iga, igd, ige, or igm

424 88, 424 91, 436539, 436547, 436824, A61K 3900

Patent

active

045646007

ABSTRACT:
Allergenic factors are isolated from antigen extracts by preparing a column with pooled serum from patients with allergy to a given allergen system and passing over this column a pool of allergen extracts from different sources. Allergen specific immunoglobulin antibodies in purified form are obtained by forming an antigen-specific antibody complex from serum containing the antibodies and a material containing the antigen, recovering the complex and disassociating it, forming a second complex of the antigen with an excess of a second antibody so as to realize a combination of the second complex, free first specific antibody and free second specific antibody and then separating the second complex from the free first and second antibodies.

REFERENCES:
patent: 2901398 (1959-08-01), Perlman
patent: 3953588 (1976-04-01), Nieschulz
patent: 3984532 (1976-10-01), de Castro
patent: 3995023 (1976-11-01), Nieschulz
patent: 4027006 (1977-05-01), Nieschulz
patent: 4031199 (1977-06-01), Nieschulz
patent: 4148869 (1979-04-01), Deaton
patent: 4226853 (1980-10-01), Marsh
patent: 4243651 (1981-01-01), Nalebuff
patent: 4256833 (1981-03-01), Ali
patent: 4350686 (1982-09-01), Relyveld
Chemical Abstracts I, 88:48843w (1978).
Chemical Abstracts II, 90:101863x (1979).

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