Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1995-06-06
1998-12-01
Grimes, Eric
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
4241851, 4242751, 530300, 530324, 530325, 530326, 530327, 530328, 530350, A61K 3935, C07K 700, C07K 1447, G01N 3353
Patent
active
058436723
ABSTRACT:
Isolated nucleic acids encoding allergens of Canis familiaris, Can f I or Can f II, are disclosed. A cDNA encoding a peptide having a Can f I activity and a predicted molecular weight of about 19,200 daltons is also described. A cDNA encoding a peptide having Can f II activity and a predicted molecular weight of about 18,200 daltons is also disclosed. The nucleic acids can be used as probes to detect the presence of Can f I or Can f II nucleic acid in a sample or for the recombinant production of peptides having a Can f I or Can f II activity. Peptides having a Can f I or Can f II activity can be used in compositions suitable for pharmaceutical administration or methods of diagnosing sensitivity to dog dander.
REFERENCES:
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Bizinkauskas Christine B.
Brauer Andrew W.
Konieczny Andrzej
Morgenstern Jay P.
Grimes Eric
Hanley Elizabeth A.
Immulogic Pharmaceutical Corporation
Mandragouras Amy E.
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