Allergenic proteins and peptides from dog dander and uses...

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Allergen or component thereof

Reexamination Certificate

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C424S184100, C424S185100, C530S350000, C530S300000, C435S069100, C435S007100, C435S325000, C536S023500

Reexamination Certificate

active

11202960

ABSTRACT:
Isolated nucleic acids encoding allergens ofCanis familiaris, Can fI or Can fII. are disclosed. A cDNA encoding a peptide having a Can fI activity and a predicted molecular weight of about 19,200 daltons is also described. A cDNA encoding a peptide having Can fII activity and a predicted molecular weight of about 18,200 daltons is also disclosed. The nucleic acids can be used as probes to detect the presence of Can fI or Can fII nucleic acid in a sample or for the recombinant production of petides having a Can fI or Can fII activity. Peptides having a Can fI or Can fII activity can be used in compositions suitable for pharmaceutical administration or methods of diagnosing sensitivity to dog dander.

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