Allergenic proteins and peptides from dog dander and uses...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C536S023100, C536S023500, C424S184100, C424S185100, C424S275100, C514S002600, C514S012200, C530S300000, C530S350000

Reexamination Certificate

active

07026128

ABSTRACT:
Isolated nucleic acids encoding allergens ofCanis familiaris,Can f I or Can f II, are disclosed. A cDNA encoding a peptide having a Can f I activity and a predicted molecular weight of about 19,200 daltons is also described. A cDNA encoding a peptide having Can f II activity and a predicted molecular weight of about 18,200 daltons is also disclosed. The nucleic acids can be used as probes to detect the presence of Can f I or Can f II nucleic acid in a sample or for the recombinant production of peptides having a Can f I or Can f II activity. Peptides having a Can f I or Can f II activity can be used in compositions suitable for pharmaceutical administration or methods of diagnosing sensitivity to dog dander.

REFERENCES:
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