Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...
Patent
1995-06-06
1999-04-06
Grimes, Eric
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
536 235, 4353201, 4352523, 43525411, C12N 121, C12N 510, C12N 1512, C12N 1563
Patent
active
058917160
ABSTRACT:
Isolated nucleic acids encoding allergens of Canis familiaris, Can f I or Can f II, are disclosed. A cDNA encoding a peptide having a Can f I activity and a predicted molecular weight of about 19,200 daltons is also described. A cDNA encoding a peptide having Can f II activity and a predicted molecular weight of about 18,200 daltons is also disclosed. The nucleic acids can be used as probes to detect the presence of Can f I or Can f II nucleic acid in a sample or for the recombinant production of petides having a Can f I or Can f II activity. Peptides having a Can f I or Can f II activity can be used in compositions suitable for pharmaceutical administration or methods of diagnosing sensitivity to dog dander.
REFERENCES:
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Bizinkauskas Christine B.
Brauer Andrew W.
Konieczny Andrzej
Morgenstern Jay P.
Grimes Eric
Hanley Elizabeth A.
Immulogic Pharmaceutical Corporation
Mandragouras Amy E.
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