Allergen-containing substances

Details Allergen-containing substances Allergen-containing substances

1977-08-08

1981-04-14

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

424177, 424 88, 424 80, 424 81, 424 89, 424 91, A61K 3174, A61K 3700

Patent

active

042619734

ABSTRACT:
This invention pertains to allergen-containing substances, methods of preparing the same and using the same as immunologically specific suppressants of the production of reaginic antibodies directed to the allergen in question. The allergen-containing substances can be characterized as covalent conjugates of the allergen molecules with non-immunogenic water-soluble polymers. The degree of conjugation is such that the conjugates are rendered tolerogenic as well as substantially non-allergenic and non-immunogenic. The new conjugates are useful for immunologically specific suppression of common allergies in mammals, including humans, which are mediated by reaginic antibodies of the IgE class.

REFERENCES:
patent: 3869546 (1975-03-01), Lund
patent: 3919411 (1975-11-01), Glass et al.
patent: 3920811 (1975-11-01), Lund

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