Allenic prostanoic acid derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters

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560 53, 560121, 562463, 562500, 562503, C07C17700

Patent

active

045785058

ABSTRACT:
This invention relates to novel allenic prostanoic acid derivatives having the following formula ##STR1## wherein R is hydrogen; or straight or branched chain alkyl of 1 to 6 carbon atoms, inclusive
wherein R.sub.1 is hydrogen; or straight or branched chain alkyl of 1 to 6 carbon atoms, inclusive; or vinyl (--CH.dbd.CH.sub.2)
wherein R.sub.2 is straight or branched chain alkyl of 1 to 6 carbon atoms; or cycloalkyl group containing 3 to 6 carbon atoms; or phenyl; or phenoxy
wherein R.sub.3 is hydrogen; or straight chain alkyl of 1 to 3 carbon atoms
wherein m is an integer of from 1 to 4, inclusive,
wherein n is an integer of from 1 to 3, inclusive with the proviso that the sum of m and n does not exceed 5,
wherein y is an integer of from 1 to 3.
These compounds are useful by reason of their gastric antisecretory and cytoprotective activity.

REFERENCES:
patent: 3879438 (1975-04-01), Crabbe et al.
patent: 4312994 (1982-01-01), Collins

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