Allene containing arachidonic acid derivatives

Details Allene containing arachidonic acid derivatives Allene containing arachidonic acid derivatives

1982-10-13

1985-05-07

Sneed, Helen M. S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2604109R, C11C 100

Patent

active

045157278

ABSTRACT:
Disclosed herein are novel allene-containing compounds of the formula ##STR1## wherein R is hydrogen, alkyl of 1 to 6 carbon atoms or a pharmaceutically acceptable salt; X is CH.dbd.CH, OCH.sub.2, CH.sub.2 O, CH.sub.2 S, SCH.sub.2, O or S; n is 1 or 2 but is 1 when X is CH.dbd.CH; m is 0-6; and the dotted lines represent a single or double bond. These compounds mediate leukotriene-caused physiological changes in mammals.

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