Allelic variants of bovine somatotropin gene:genetic marker for

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 911, 935 77, 935 78, 536 235, 536 2351, 536 2433, C12Q 168, C12P 1934, C07H 1700

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053745230

ABSTRACT:
An assay for determining the presence in bovine genetic material of a genetic marker located on the bovine somatotropin gene indicative of an inheritable trait of increased milk production is provided. The marker is a polymorphism in the gene encoding somatotropin at amino acid position 126 which results in two forms of somatotropin existing in bovine. The assay comprises analyzing a bovine to determine its genotype with respect to the somatotropin gene. Bovine with the desired marker can be selected for inclusion in breeding programs or for milking. The desired marker indicative of superior milk production is dependent upon the breed of cattle. Holstein cattle that are homozygous for the leucine forms of somatotropin are desired. Jersey cattle that are homozygous for the valine form of somatotropin are desired. A kit for performing the assay is also provided.

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