Alleles of the PRPD1 gene from coryneform bacteria

Details Alleles of the PRPD1 gene from coryneform bacteria Alleles of the PRPD1 gene from coryneform bacteria

2011-02-22

2011-02-22

Noakes, Suzanne M (Department: 1656)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S252300, C435S252320, C435S252800, C435S320100, C435S069100, C435S071100

Reexamination Certificate

active

07893231

ABSTRACT:
An isolated mutant of coryneform bacteria comprising a gene encodes a polypeptide having 2-methylcitrate dehydratase activity, where the polypeptide comprises an amino acid sequence in which one of the proteinogenic amino acids except L-proline is present at position 272 or a corresponding or comparable position. In addition, an isolated polynucleotide encoding a polypeptide having 2-methylcitrate dehydratase enzymic activity, which comprises at position 272 of the amino acid sequence or a corresponding or comparable position a proteinogenic amino acid except L-proline is described. A method for producing a recombinant coryneform bacterium and L-amino acids. A recombinant microorganism, L-Lysine-containing feed additive, and L-Tryptophan-containing feed additive is also described.

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