Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...
Reexamination Certificate
2005-09-16
2008-03-04
Prouty, Rebecca E. (Department: 1652)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing alpha or beta amino acid or substituted amino acid...
C435S108000, C435S114000, C435S252300, C435S252320, C435S113000, C435S190000, C435S320100, C435S471000, C435S252330, C536S023200
Reexamination Certificate
active
07338790
ABSTRACT:
The invention relates to mutants and alleles of the gnd gene from coryneform bacteria coding for 6-phosphogluconate dehydrogenases which contain at position 329 or a comparable position of the amino acid sequence any amino acid other than L-valine, and to processes for the production of amino acids, preferably L-lysine and L-tryptophan, by fermentation using bacteria that contain these alleles.
REFERENCES:
patent: 6822085 (2004-11-01), Farwick et al.
patent: 2004/0063181 (2004-04-01), Duncan et al.
patent: 2006/0246554 (2006-11-01), Thierbach et al.
patent: 1 462 516 (2004-09-01), None
patent: WO 01/71012 (2001-09-01), None
Yousuke Nishio, et al., “Comparative Complete Genome Sequence Analysis of the Amino Acid Replacements Responsible for the Thermostability of Corynebacterium efficiens”, Genome Research, XP-002995065, 2003, pp. 1572-1579 and 2 pages of DATABASE UniProt, AN Q8FTI1, XP-002375536, Mar. 1, 2003.
A. M. Cerdeno-Tarraga, et al., “The complete genome sequence and analysis ofCorynebacterium diphteriaeNCTC13129”, Nucleic Acids Research, vol. 31, No. 22, XP-002375534, Nov. 15, 2003, pp. 6516-6523 and 2 pages of DATABASE UniProt, AN Q6NHC5, XP-002375537, Jul. 5, 2004.
U.S. Appl. No. 11/227,138, filed Sep. 16, 2005, Thierbach et al.
U.S. Appl. No. 60/294,223, filed May 31, 2001, Farwick et al.
Bathe Brigitte
Schischka Natalie
Thierbach Georg
Degussa AG, Intellectual Property Management
Meah Md. Younus
Oblon & Spivak, McClelland, Maier & Neustadt P.C.
Prouty Rebecca E.
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