Allantoin-containing skin cream

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C424S400000, C424S401000, C424S405000, C424S070220, C424S070310, C424S070240, C514S939000, C514S940000, C514S941000, C514S943000, C514S938000

Reexamination Certificate

active

06864274

ABSTRACT:
An allantoin-containing skin cream composition can comprise allantoin and at least one anionic or nonionic emulsifier that is substantially hydrophilic and is soluble in water. The pH of the composition is in a range of from about 3.0 to about 6.0; preferably, the pH of the composition is from about 5.0 to about 6.0. The composition can further comprise an acidic anionic polymer. A preferred acidic anionic polymer is a carboxypolymethylene polymer. The composition can further comprise a carbohydrate polymer such as galactoarabinan, polygalactose or polyarabinose. The composition can additionally comprise other ingredients such as herbal extracts, an antioxidant component, an emollient component, a chelator, a solvent component, or a preservative component. The composition is useful as a skin protectant.

REFERENCES:
patent: 3830824 (1974-08-01), Margraf
patent: 3830825 (1974-08-01), Margraf
patent: 3830908 (1974-08-01), Klippel et al.
patent: 3856805 (1974-12-01), Margraf
patent: 3930000 (1975-12-01), Margraf
patent: 3932627 (1976-01-01), Margraf
patent: 3954989 (1976-05-01), Mecca
patent: 4170229 (1979-10-01), Olson
patent: 4184978 (1980-01-01), France et al.
patent: 4278664 (1981-07-01), Van Cleave
patent: 4374766 (1983-02-01), Puchalski et al.
patent: 4478853 (1984-10-01), Chaussee
patent: 4507279 (1985-03-01), Okuyama et al.
patent: 4670263 (1987-06-01), Noorlander
patent: 4707354 (1987-11-01), Garlen et al.
patent: 4708813 (1987-11-01), Snyder
patent: 4767618 (1988-08-01), Grollier et al.
patent: 4806262 (1989-02-01), Snyder
patent: 4822601 (1989-04-01), Goode et al.
patent: 4880621 (1989-11-01), Grollier et al.
patent: 4933177 (1990-06-01), Grollier et al.
patent: 4981845 (1991-01-01), Pereira
patent: 5112886 (1992-05-01), Phalangas
patent: 5122533 (1992-06-01), Bar-On et al.
patent: 5176916 (1993-01-01), Yamanaka et al.
patent: 5221533 (1993-06-01), Perlman
patent: 5455033 (1995-10-01), Silverman et al.
patent: 5476664 (1995-12-01), Robinson et al.
patent: 5512200 (1996-04-01), Garcia
patent: 5567427 (1996-10-01), Papadakis
patent: 5578312 (1996-11-01), Parrinello
patent: 5616347 (1997-04-01), Alliger et al.
patent: 5658559 (1997-08-01), Smith
patent: 5661170 (1997-08-01), Chodosh
patent: 5709847 (1998-01-01), Bissett et al.
patent: 5736128 (1998-04-01), Chaudhuri et al.
patent: 5753245 (1998-05-01), Fowler et al.
patent: 5824666 (1998-10-01), Deckner et al.
patent: 5827870 (1998-10-01), Chodosh
patent: 5830483 (1998-11-01), Seidel et al.
patent: 5849310 (1998-12-01), Trinh et al.
patent: 5863548 (1999-01-01), Elder
patent: 5871754 (1999-02-01), Briggs et al.
patent: 5871762 (1999-02-01), Venkitaraman et al.
patent: 5876736 (1999-03-01), Cohen et al.
patent: 5885581 (1999-03-01), Massand
patent: 5914116 (1999-06-01), Suares et al.
patent: 5932228 (1999-08-01), Hall et al.
patent: 5952373 (1999-09-01), Lanzendörfer et al.
patent: 5958436 (1999-09-01), Hahn et al.
patent: 5968528 (1999-10-01), Deckner et al.
patent: 6001377 (1999-12-01), SaNogueira, Jr. et al.
patent: 6060061 (2000-05-01), Breton et al.
patent: 6077520 (2000-06-01), Tominaga
patent: 6080393 (2000-06-01), Liu et al.
patent: 6086903 (2000-07-01), Trinh et al.
patent: 6120782 (2000-09-01), Mansouri
patent: 6169114 (2001-01-01), Yamaguchi et al.
patent: 6174533 (2001-01-01), SaNogueira, Jr. et al.
patent: 6281236 (2001-08-01), Farber
patent: 6306915 (2001-10-01), Murata
patent: 6329413 (2001-12-01), Farber
patent: 6337065 (2002-01-01), Jacobson et al.
patent: 0242553 (1987-10-01), None
patent: 0380157 (1990-08-01), None
patent: 1346544 (1974-02-01), None
patent: 358140013 (1983-08-01), None
patent: WO 9009779 (1990-09-01), None
JP 58-1400013, 1983, English Translation.*
R. Cahen & A. Pessonnier, “Etude Pharmacologique de L'Allantoïnate de Dihydroxyaluminium et de L'Allantoïnate de Chlorhydroxyaluminium. I.—Toxicité,”Ann. Pharm. Franç. 20:623-636 (1962) (in French), discloses the physical and chemical properties and the toxicity of dihydroxyaluminum allantoinate and chlorhydroxyaluminum allantoinate. The compounds were observed to have no toxicity.
R. Cahen & J.-F. Clement, “Etude Pharmacologique de L'Allantoïnate de Dihydroxyaluminium et de L'Allantoïnate de Chlorhydroxyaluminium. II.—Etude de l'Activité Gastrique,”Ann Pharm. Franç. 20:693-703 (1962) (in French), discloses the activity of dihydroxyaluminum allantoinate and chlorhydroxyaluminum allantoinate on gastric activity. The compounds were found to have acid-neutralizing and buffering activity and to diminish gastric acidity.
R. Cahen & A. Pessonnier, “Etude Pharmacologique de L'Allantoïnate de Dihydroxyaluminium et de L'Allantoïnate de Chlorhydroxyaluminium. III.—Effet Anti-ulcéreux,”Ann. Pharm. Franç. 20:704-713 (1962) (in French), discloses the anti-ulcer activity of the compounds dihydroxyaluminum allantoinate and chlorhydroxyaluminum allantoinate. The compounds were found to have anti-ulcer activity in rats and guinea pigs comparable to compounds such as aluminum hydrate and bismuch subnitrate.
R. Cahen & A. Pessonnier, “Etude Pharmacologique de L'Allantoïnate de Dihydroxyaluminium et de L'Allantoïnate de Chlorhydroxyaluminium. IV.—Effet sur I'Ulcère Médicamenteux Expérimental,”Ann. Pharm. Franç. 21:215-222 (1963) (in French), discloses the effect of the compounds dihydroxyaluminum allantoinate and chlorhydroxyaluminum allantoinate on ulcers produced in the rat by administration of phenylbutazone or reserpine. The compounds were found to have activity against such ulcers.
C. Debray et al., “Etude de Dèrivés Allantoïniques de l'Aluminium dans la Thérapeutique des Affections Gastro-duodénales,”Presse Méd. 70:2643-44 (1962) (in French) discloses the activity of the compounds dihydroxyaluminum allantoinate and chlorhydroxyaluminum allantoinate administered in a complex with a polymer of polyoxyethylene and polyoxypropanediol, methylhomatropine bromide, and calcium carbonate on gastrointestinal conditions. The complex was said to be effective against duodenal ulcer and effective in protecting the gastric mucosa.
Japan Patent Publication to Abe et al. (abstract only), Jul. 29, 1992, JP 404208219.
Japanese patent publication No. JP 58140013 A by Daiichi Seiyaku Co., published Aug. 19, 1983.
Publication—product information insert for Alphosyl Cream and Alphosyl Lotion, G.D. Searle (South Africa), Apr. 24, 1975.
Publication—product information insert for Clearasil Medicated Facial Cleanser, Procter & Gamble (South Africa) Jan. 31, 1994.
Publication—product information insert for Arola Rosebaum, Supramed Limited, Jan. 12, 1986.
Abstract of a publication—M. Cajkovac et al., “Influence of Emulsoid Vehicle on the Release and Activity of Allantoin,”Pharmazie47: 39-43 (1992) (abstract only).
Abstract of a publication—M. Maragakis et al., “Possibilities of Scar Treatment After Thoracic Surgery,”Drugs Under Exp. &Clin. Res.21: P199-206 (1995) (abstract only).
Publication product information insert for Alphosyl, undated (1975).
Abstract of a publication—G. Stinco et al., “Seborrheic Dermatitis Treated with Furalglucitole Cream,”Dermatol. Clin.18: 78-81 (1998) (abstract only).
Abstract of a publication—M. Maragakis et al., “Possibilities of Scar Treatment After Thoracic Surgery,”Drugs Exp. Clin. Res.21: P:199-206 (1999) (abstract only).
Abstract of a publication—G.H. Willital & H. Heine, “Efficiency of Contractubex® Gel in the Treatment of Fresh Scars After Thoracic Surgery in Children and Adolescents,”Int. J. Clin. Pharmacol. Res.14: 193-202 (1994) (abstract only).
Publication, H.W. Margraf & T.H. Covey, Jr., “A Trial of Silver-Zinc-Allantoinate in the Treatment of Leg Ulcers,”Arch. Surg.12: 699-704 (1977).
Publication, Remington: The Science and Practice of Pharmac

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