Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1991-06-12
1992-09-29
Brown, Johnnie R.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 24, 536 26, 536 27, 536 29, 544243, 544244, C07H 100
Patent
active
051515075
ABSTRACT:
Alkynylamino-nucleotides and labeled alkynylaminonucleotides useful, for example, as chain terminating substrates for DNA sequencing are provided along with several key intermediates and processes for their preparation. For some applications, longer, hydrophilic linkers are provided.
REFERENCES:
patent: 5047519 (1991-09-01), Hobbs, Jr. et al.
Bergstrom et al., J. Am. Chem. Soc., vol. 98; p. 1587 (1976).
Langer et al., Proc. Natl. Acad. Sci., U.S.A., vol. 78; No. 11, pp. 6633-6637.
Draper, Nucleic Acid Research; vol. 12, No. 2, 989-1022 (1984).
Barr et al., J. Chem. Soc.; Perkins Trans I, pp. 1263-1267 (1978).
Bergstrom et al., J. Am. Chem. Soc.; vol. 100, p 8106 (1978).
Vincent et al., Tetrahedron Letters, vol. 22, pp. 945-947 (1981).
Robins et al., J. Org. Chem.; vol. 48, 1854-1862 (1983).
Sonogashira et al., Tetrahedron Letters; No. 50, pp. 4467-4470 (1975).
Edo et al., Chem. Pharm. Bull.; vol. 26, No. 12, pp. 3843-3850 (1978).
Seda et al., Chem. Bor., vol. 11; 2925-2930 (1978).
Schram et al., J. Carbohyd., Nucles., Nucleotis, vol. 2, No. 2, pp. 177-184 (1975).
Bergstrom et al., J. Org. Chem., vol. 46, No. 7; pp. 1423-1431 (1981).
Bergstrom et al., Nucleic Acid Research, vol. 8; pp. 6213-6219 (1980).
Haralambidis et al., Nucleic Acid Research, vol. 15, No. 12, pp. 4857-4867 (1987).
Gibson et al., Nucleic Acid Research, vol. 15, No. 16, pp. 6455-6467 (1987).
Hobbs, Jr. Frank W.
Trainor George L.
Brown Johnnie R.
E. I. Du Pont de Nemours and Company
Frank George A.
Wilson J. Oliver
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