Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1999-08-26
2000-11-21
Seaman, D. Margaret
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546157, 546158, A61K 3147, C07D21516, C07D21520, C07D21536
Patent
active
061503770
ABSTRACT:
The present invention relates to compounds of formula 1 and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, R.sup.9, R.sup.10, and R.sup.11 are as defined herein. The above compounds of formula 1 are useful in the treatment of hyperproliferative disorders, such as cancer, in mammals. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of inhibiting abnormal cell growth, including cancer, in a mammal by administering the compounds of formula 1 to a mammal requiring such treatment.
REFERENCES:
patent: 5747498 (1998-05-01), Schnur
patent: 5968952 (1999-10-01), Venet
patent: 6037350 (2000-03-01), Venet
La Greca Susan D.
Lyssikatos Joseph P.
Ginsburg Paul H.
Looney Adrian G.
Pfizer Inc.
Richardson Peter C.
Seaman D. Margaret
LandOfFree
Alkynyl-substituted quinolin-2-one derivatives useful as antican does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Alkynyl-substituted quinolin-2-one derivatives useful as antican, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Alkynyl-substituted quinolin-2-one derivatives useful as antican will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1257625