Alkynyl and azido-substituted 4-anilinoquinazolines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

544283, 544293, A61K 31495, A61K 31505, C07D23970, C07D23994

Patent

active

057474982

ABSTRACT:
The invention relates to compounds of the formula ##STR1## and to pharmaceutically acceptable salts thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, n and m are as defined herein. The compounds of formula I are useful in the treatment of hyperproliferative diseases, such as cancer. The invention further relates to processes of making the compounds of formula I and to methods of using such compounds in the treatment of hyperproliferative diseases.

REFERENCES:
patent: 5256781 (1993-10-01), Primeau
patent: 5457105 (1995-10-01), Barker
patent: 5475001 (1995-12-01), Barker

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