Alkylsulphonamide quinolines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C546S159000

Reexamination Certificate

active

07608628

ABSTRACT:
Compounds of Formula IIwherein R1, A, R2, R3, R4, R5, R8, n, m and q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.

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Giardina et al.: Discovery of a novel class of selective non-peptide antagonists for the human neurokinin-3 receptor. 2. Identification of (S)-(N)-(1-phenylpropyl)-3-hydroxy-2-phenylquinoline-4-carboximide (SB 223412). J Med Chem, 42:1053-1065, 1999.
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