Alkylsulfonamidophenylalkylamines

Details Alkylsulfonamidophenylalkylamines Alkylsulfonamidophenylalkylamines

1984-10-15

1986-02-11

Waltz, Thomas A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26050119, 2605011, 564 99, 514605, C07C14375, A61K 3118

Patent

active

045698015

ABSTRACT:
The present invention relates to a new class of alkylsulfonamidophenylalkylamines which are potent antiarrhythmic agents having good oral bioavailability properties.

REFERENCES:
patent: 3574741 (1971-04-01), Gould
patent: 4289787 (1981-09-01), Molloy et al.
patent: 4336269 (1982-06-01), Molloy et al.
Uloth et al., J. of Med. Chem. 9(1), pp. 88-97 1966.
Riggilo et al., J. of Pharmacol. Exp. Ther. 1968 163(1), pp. 25-35.
Somani et al., The Journal of Pharmacology and Experimental Therapeutics 164, No. 2, 317 (1968).
Barlow et al., British Journal of Pharmacology 37, 555 (1969).
Holland et al., J. Med. Chem. 6, 521 (1963).

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