Alkylenedioxyphenyl ether derivatives having anti-ischaemic, mem

Details Alkylenedioxyphenyl ether derivatives having anti-ischaemic, mem Alkylenedioxyphenyl ether derivatives having anti-ischaemic, mem

1992-03-17

1994-01-25

Tsang, Cecilia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514254, 514255, 514317, 514321, 514327, 544377, 544398, 544401, 546197, 546217, 546236, A61K 31495, A61K 31445, C07D40504, C07D40506

Patent

active

052815951

ABSTRACT:
The invention relates to compounds having anti-ischaemic activity, memory enhancing activity and anti-convulsive activity of the formulae 1A and 1B ##STR1## wherein R.sub.1 +R.sub.2 together form an alkylene group having 1-3 C-atoms which may be substituted with one or more alkyl group(s) having 1-3 C-atoms and the remaining R and Z variables are defined as disclosed herein, or a pharmacologically acceptable salt thereof.

REFERENCES:
patent: 3996279 (1976-12-01), Schlager
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patent: 4535159 (1985-08-01), Forne et al.
patent: 4574156 (1986-03-01), Morita et al.
Patents Abstracts of Japan, vol. 14, No. 208 (C-714) (4151) Apr. 27, 1990 & JP-A-245464 (Mejji Seika Kaisha Ltd.).
Chemical & Pharmaceutical Bulletin, vol. 35, No. 8, Aug. 1987 pp. 3270-3275; JP; H. Ohtaka et al, "Benzylpiperazine Deriva . . . ".
Chemical & Pharmaceutical Bulletin, vol. 35, No. 7, Jul. 1987 pp. 2774-2781; JP; H. Ohtaka et al, "Benzylpiperazine Deriv . . . ".
Chemical & Pharmaceutical Bulletin, vol. 35, No. 7, Jul. 1987 pp. 2782-2791; JP; H. Ohtaka et al, "Benzylpiperazine Deriv . . . ".

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