Alkylenediamine derivatives

Details Alkylenediamine derivatives Alkylenediamine derivatives

1990-08-01

1991-12-03

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

540609, 546246, 548569, C07D22504, C07D23304, C07D21114, C07D20704

Patent

active

050701967

ABSTRACT:
Novel alkylenediamine derivatives effectively employable as glutamate blockers have the formula (I) or (II): ##STR1## wherein each of R.sup.1 and R.sup.6 is an aliphatic hydrocarbon group, an alicyclic hydrocarbon group, an aryl group, or an aralkyl group; each of R.sup.2 and R.sup.7 is an aliphatic hydrocarbon group, an alkoxy group, an aliphatic hydrocarbon group containing an ester bonding, an aliphatic hydrocarbon group containing an ether bonding, or an aryloxy group; each of R.sup.3, R.sup.4, R.sup.5, R.sup.8, R.sup.9 and R.sup.10 is hydrogen, an alkyl group, an alkoxy group, an acyloxy group, an aryl group, an aralkyl group, hydroxyl, a hydroxylalkyl group, halogen, nitrile, nitro, amino, carbamoyl or alkoxycarbonyl; and each of m and n is an integer of 0-3 (m+n does not exceed 3); k is an integer of 1-4; each of p and i is an integer of 2-13; and each of q and j is an integer of 4-7.

REFERENCES:
patent: 3371093 (1968-02-01), Zenitz et al.
patent: 3712896 (1973-01-01), Tilford et al.
E. Szarvasi et al., Bull. Soc. Chem. France 6 (1966), 1838-1846.

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