Alkylcarbamoylborane cyclic dimers

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

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562624, C07F 502

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active

051965810

ABSTRACT:
Alkylcarbamoylborane cyclic dimers are synthesized through reactions of alkylcarbamoylborane adducts of amines. The inventive dimers have utility as reactants in the direct synthesis of alkylcarbamoylborane adducts of primary and secondary amines. Alkylcarbamoylborane adducts of primary and secondary amines and certain of the inventive dimers have biological activity as anti-tumor, hypocholesteremic, and anti-inflammatory agents. The cyclic dimers of this invention have the formula [BHRC(O)NHR'].sub.2, examples of which include:

REFERENCES:
patent: 4312989 (1982-01-01), Spielvogel et al.
patent: 4368194 (1983-01-01), Spielvogel et al.
patent: 4587359 (1986-05-01), Spielvogel et al.
patent: 4855493 (1989-08-01), Spielvogel et al.

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