Alkylated styrenes as prodrugs to COX-2 inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514255, 514256, 514307, 514317, 514357, 514365, 514374, 514406, 514427, 514438, 514461, 544179, 544224, 544242, 544336, 546141, 546236, 546237, 546238, 546300, 546301, 548204, 548236, 548253, 5483731, 5483751, 548482, 548560, 548561, 549 77, 549 79, 549 80, 549496, C07D20944, C07D21330, C07D21716, C07D21122, C07D30732, A61K 3144, A61K 31445, A61K 3147

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active

059256311

ABSTRACT:
The invention encompasses the novel compound of Formula I useful in the treatment of cyclooxygenase-2 mediated diseases. ##STR1## The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula I.

REFERENCES:
patent: 5393790 (1995-02-01), Reitz et al.

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