Alkylated bicycloalkaneamines for treatment of neurotoxic injury

Details Alkylated bicycloalkaneamines for treatment of neurotoxic injury Alkylated bicycloalkaneamines for treatment of neurotoxic injury

1987-10-23

1989-06-06

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514659, A61K 3113, A61K 31135

Patent

active

048372188

ABSTRACT:
Compounds, compositions and methods of treatment are described to control brain damage associated with anoxia or ischemia which typically follows such conditions as stroke, cardiac arrest or perinatal asphyxia. The treatment includes administration of an alkylated bicycloalkaneamine compound as an antagonist to inhibit excitotoxic actions at major neuronal exzcitatory amino acid receptor sites.

REFERENCES:
Chem. Abst. 107-51624s (1987).

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