Alkylammonium complexes of diatrizoic acid as X-ray contrast age

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure

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26050116, 424 4, 562456, A61K 4904, C07C 6368

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active

047357959

ABSTRACT:
New X-ray contrast agents are provided which are alkylammonium complexes of diatrizoic acid having the structure ##STR1## X-ray contrast medium containing the above X-ray contrast agent and a carrier therefor such as a liposome carrier, and a method for the X-ray visualization of body cavities and organs are also provided.

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Chemical Abstract, vol. 95, No. 138626b, 1981, Baldeschweiler et al, "Lipid Vesicles Bearing Carbohydrate Surfaces as Lymphatic Directed Vehicles".
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Havron et al, "Radiopaque Liposomes: A Promising New Contrast Material for Computed Tomography of the Spleen", Radiology 140:507-511, Aug., 1981.
Ryan et al, "The Preparation and Characterization of Liposomes Containing X-ray Contrast Agents", Biochemica et Biophysica Acta. 756 (1983), 106-110 (Elsevier Biomedical Press).

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